Two sample MR report
C19orf60_Monocyte (Mono) against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | 0.0654688 | 0.3765809 | 0.8779876 |
| Weighted median | 4 | 0.0297358 | 0.0155632 | 0.0560497 |
| Inverse variance weighted | 4 | 0.0283062 | 0.0135230 | 0.0363328 |
| Simple mode | 4 | 0.0309688 | 0.0201189 | 0.2213623 |
| Weighted mode | 4 | 0.0311743 | 0.0194189 | 0.2067611 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1034580 | 2 | 0.9495862 |
| Inverse variance weighted | 0.1132091 | 3 | 0.9902065 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0163717 | 0.1657929 | 0.9303443 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 6.83e-05 | 0 | TRUE | 0.4321479 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
